Hi,
I'll answer this question for you now, but you must first understand the relationship between adwords and adsense. The ads that pay the most for adsense are typically the keywords that cost the most on adwords.
What is the Google Adwords program?
Google AdWords is a quick and simple way to purchase highly targeted cost-per-click (CPC) advertising, regardless of your budget. AdWords ads are displayed along with search results on Google, as well as on search and content sites in our growing ad network, including AOL, EarthLink, HowStuffWorks, & Blogger. With more than 200 million searches on Google each day and even more searches and page views on our ad network, your Google AdWords ads reach a vast audience.
When you create a Google AdWords ad, you choose keywords for which your ad will appear and specify the maximum amount you're willing to pay for each click. You only pay when someone clicks on your ad. To save you even more money, the AdWords Discounter automatically reduces the actual CPC you pay to the lowest cost needed to maintain your ad's position on the results page.
What is the Google Adsense program?
Google AdSense is a fast and easy way for website publishers of all sizes to display relevant, text-based, un-obtrusive Google AdWords™ ads on their website's content pages and earn money. Because the ads are related to what your users are looking for on your site, you'll finally have a way to both monetize and enhance your content pages.
How does Google target ads to my website?
Simply put, Google provides you with AdSense HTML ad code to place on the web pages on which you want to display AdWords ads. Then, they take care of the rest by leveraging award-winning and proprietary Google search and page-ranking technologies to deliver relevant AdWords ads to those content pages.
Google goes beyond simple keyword matching to understand the context and content of web pages. Based on a sophisticated algorithm that includes such factors as keyword analysis, word frequency, font size, and the overall link structure of the web, they know what a page is about, and can precisely match Google ads to each page.
What you need to know is what keywords cost the most for the adwords program. If you know these keywords, then you can design you websites around them you maximum payouts.
These sites list the top paying keywords.
http://www.rumler.com/google/adsense/top-paying-keywords.php
and
http://www.vaughns-1-pagers.com/internet/top-paying-words.htm
Now, if you really want to make money using the adsense program I suggest you goto ==> http://ebizac.com/x/t.php/4268
You will find all the tips and secrets needed to really strike it rich on line.
I hope this helps !